GluR1a (Glutamate Receptor)

Cat no: G3500-06F1

Supplier: United States Biological

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metabotropic glutamate receptor 1a (mGluR1a). The metabotropic glutamate receptors have been organised into three groups. mGluR5 and mGluR1 make up group I which, when activated, stimulates phospholipase C and activates protein kinase C to hydrolyse phosphoinositide phospholipids in the cell membrane. Group I mGluRs, but not other groups, are activated by 3, 5-dihydroxyphenylglycine (DHPG). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1,000 Immunohistochemistry (frozen):1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	G3500-06F1
Reactivities:	Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ul
Form:	Supplied as a liquid in10mM HEPES, pH 7.5, 150mM sodium chloride, 0.01% BSA, 50% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes rat metabotropic glutamate receptor 1a at ~125kD (monomer) and 250kD (dimer) in HEK293 cells.

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GluR1a (Glutamate Receptor)

Cat no: G3500-06F1

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