GluR2 (Ser880) Antibody

Cat no: 252549

Supplier: ABBIOTEC

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Description
Additional Information

The glutamate receptor 2, a homo- or heter0teramer, is an Ionotropic glutamate receptor. L-glutamate acts as an e, Xenopus/Amphibian,citatory neurotransmitter at many synapses in the central nervous system. Binding of the e, Xenopus/Amphibian,citatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Ser880 has been identified as a PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1.

Catalogue number:	252549
Reactivities:	Human, Mouse, Chicken/Bird, Rabbit, Zebrafish/Fish
Applications:	Western Blot
Size:	0.1 ml
Accession:	P19491
Antigen:	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser880 of rat GluR2-subunit.
Format:	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype:	Rabbit IgG
Additional info:	Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2; Gria2; Glur2