Home  >  Products  >  GluR3 (Glutamate Receptor 3, GluR3, GluR-3, AMPA-selective Glutamate Receptor 3, AMPA3, GLURC, GluR-C, GluR-K3, Ionotropic Glutamate Receptor AMPA 3, Gria3, MRX94)
GluR3 (Glutamate Receptor 3, GluR3, GluR-3, AMPA-selective Glutamate Receptor 3, AMPA3, GLURC, GluR-C, GluR-K3, Ionotropic Glutamate Receptor AMPA 3, Gria3, MRX94)

GluR3 (Glutamate Receptor 3, GluR3, GluR-3, AMPA-selective Glutamate Receptor 3, AMPA3, GLURC, GluR-C, GluR-K3, Ionotropic Glutamate Receptor AMPA 3, Gria3, MRX94)

Cat no: G3500-19E

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
AMPA- (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainite- and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Post-transcriptional modifications (alternative splicing and nuclear RNA editing) and post-translational modifica- tions (glycosylation, phoshorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs (1). GluR 3 knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission (2). Aberrant GluR 3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Rett
Catalogue number: G3500-19E
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in 10mM sodium HEPES pH 7.5, 150mM NaCl, 0.1mg/ml BSA, 0.02% sodium azide and 50% glycerol.
P type: Mab
Isotype: IgG
Purity: Purified
Additional info: Recongnizes endogenous levels of human total GluR 3 protein. Species crossreactivity: mouse, rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave