Home  >  Products  >  GLUR4, ID (Glutamate Receptor 4, GluR-4, GluR4, AMPA-selective Glutamate Receptor 4, GluR-D, Glutamate Receptor Ionotropic, AMPA 4, GluA4, GRIA4)
GLUR4, ID (Glutamate Receptor 4, GluR-4, GluR4, AMPA-selective Glutamate Receptor 4, GluR-D, Glutamate Receptor Ionotropic, AMPA 4, GluA4, GRIA4)

GLUR4, ID (Glutamate Receptor 4, GluR-4, GluR4, AMPA-selective Glutamate Receptor 4, GluR-D, Glutamate Receptor Ionotropic, AMPA 4, GluA4, GRIA4)

Cat no: G3500-23

Supplier: United States Biological
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Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GRIA4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer. Applications: Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.3ug/ml ELISA: 0.1-0.3ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G3500-23
Reactivities: Human
Hosts: Goat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human Gria4. Species sequence homology: Bovine, mouse and rat.

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