GLUT 2 (Glucose Transporter, Insulin Regulatable)

Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-7, Mol. Wt. 40-60 kD) and Sodium glucose co-transporter-1 (SGLT-1, 662 amino acids; ~75 kD). Individual members of this family have identical predicted secondary structures with 12 transmembrane domains. Both N and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications have not been tested.\n\nRecommended Dilution:\nWestern Blot: 1:1000-1:5000 using chemiluminescent detection.\nELISA: 1:10,000-1:50,000. G3900-15F Control peptide can be used to coat ELISA plates at 1ug/ml.\nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

G3900-15

Size

50ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Rat

Form

Supplied as a liquid, 0.05% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

References

1. Thorens, B, et al (1988) Cell, 55, 281-290; 2. Asano, T et al (1989) Nucleic Acid Res. 17, 6386; Suzue, K., et al (1989) Nucleic Acid Res. 17, 10099.

Additional Info

Recognizes rat Glut-2.