Glyceraldehyde 3-Phosphate Dehydrogenase, Human (GAPD, GAPDH, G3PD, MGC88685)

Supplier:

United States Biological

Cat no: G8140-14

Glyceraldehyde 3-Phosphate Dehydrogenase, Human (GAPD, GAPDH, G3PD, MGC88685)

Glyceraldehyde-3-phosphate dehydrogenase,G3PDH/GAPD/G3PD (EC 1.2.1.12) catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). G3PDH is a cytosolic enzyme. It is thought to be a tetramer of identical chains ~36kD. G3PDH (mouse/rat/rabbit 333; human 335-aa,chromosome 12p13.31-p13.1). The enzyme is present in such widely separated forms as man, lobster, and E. coli. Its rate of evolutionary change is one of the slowest known. \n\nApplications:\nSuitable for use as an antigen. Other applications not tested.\n\nRecommended Dilution: \nOptimal dilutions to be determined by researcher.\n\nStorage and Stability:\nAliquot and store at 4 degrees C. Do not freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

G8140-14

Size

100ug

Form

Supplied as a liquid in 80% ammonium sulfate, containing traces of HEPES, EDTA, and DTT. No preservatives added.

Purity

Highly purified ((same/more than) 98% by SDS-PAGE).

References

1. Tso JY et al (1985) Nucl. Acid Res. 13, 2485-2502;\n2.Hanuer A et al (1984) EMBO J. 3, 2627-2633;\n3. Arcari P et al (1984) Nucl. Acid. Res. 12, 9179-9189;\n4. Meyer-Sigler K et al (1991) PNAS 88, 8460-8464;\n5. Tokunaga K et al (1987) Cancer Res. 47, 5616-5619;\n6. Allen RW et al (1987) JBC 262, 649-653\n7. Ralser M., et al. (2007).J Biol 21;6(4):10\n8. Tisdale Ej., et al. (2007).Traffic. 8;(6):733-41

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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