Glycerophospholipids are phospholipids based on glycerol, serving as the main components of biological membranes. The diversity of head groups, complex acyl chain combinations, and a broad range of ionization efficiencies pose significant challenges for the accurate quantification of glycerophospholipids. These compounds encompass hundreds of analytes commonly encountered in routine analysis and over a thousand species identified through repeated fragmentation scans of some samples.
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