Glycine Receptor Antibody

Cat no: 253165

Supplier: ABBIOTEC

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Description
Additional Information

Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission. The binding of glycine to its receptor produces a large increase in chloride conductance, which causes membrane hyperpolarization. Glycine receptors are anchored at inhibitory chemical synapses by a cytoplasmic protein, gephyrin. The glycine receptor has been used to great advantage in the identification of the binding sites for alcohol on the LGIC family of proteins.

Catalogue number:	253165
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P07727
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of rat glycine receptor.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Glycine receptor subunit alpha-1; Glycine receptor 48 kDa subunit; Glycine receptor strychnine-binding subunit; Glra1; Glyr