GM-CSF, Recombinant, Rat (Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha)

Supplier:

United States Biological

Cat no: 143350

GM-CSF, Recombinant, Rat (Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha)

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells.It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes.GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells.The human and murine molecules are species-specific and exhibit no cross-species reactivity.Recombinant rat GM-CSF is a 14.5kD globular protein consisting of 128 amino acids residues.\n\nBiological Activity:\nThe ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is ~0.01ng/ml, corresponding to a specific activity of ~1.0x10e8 units/mg.\n\nAA Sequence:\nMAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK\n\nCrossreactivity:\nMouse\n\nQuality Control:\nVerified by N-terminal and Mass Spectrometry analyses (when applicable).\n\nEndotoxin:\n<0.1ng/ug of protein (<1EU/ug).\n\nProtein Content:\nVerified by UV Spectroscopy and/or SDS-PAGE gel.\n\nStorage and Stability:\nStore lyophilized products at -20 degrees C. For reconstituted solutions of most products, we recommend short-term storage at 4 degrees C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20 degrees C. Additional freeze/thaw cycles may cause some denaturation of the protein.

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SPECIFICATIONS

Catalog Number

143350

Size

5ug

Form

Supplied as a lyophilized powder.

Purity

(same/more than)98% by SDS-PAGE gel and HPLC analyses.

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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