GMFB, Recombinant, Human (Glia Maturation Factor beta, GMF-beta)

Supplier:

United States Biological

Cat no: G2035-65E

GMFB, Recombinant, Human (Glia Maturation Factor beta, GMF-beta)

Glia Maturation Factor-Beta (GMF-Beta) is a 17kD protein nerve growth factor identified as a growth and differentiation factor in the vertebrate brain. Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression. GMF-beta enhances the phenotypic expression of glia & neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Cell- surface GMF-Beta acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells.\n\nSource:\nRecombinant corresponding to human GMF-Beta expressed in E. coli. \n\nAA Sequence: SESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH\n\nMolecular Weight: \n~17kD\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

G2035-65E

Size

10ug

Form

Supplied as a lyophilized powder from 20mM PBS, pH 7.4, 130mM sodium chloride. Reconstitute with sterile dH2O to (same/more than)100ug/ml.

Purity

~98% (SDS-PAGE, HPLC)

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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