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Goat anti-Glutathione-S-Transferase Polyclonal antibody

Cat no: DPAB0537


Supplier: Creative Diagnostics
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Goat anti-Glutathione-S-Transferase Polyclonal antibody for WB. Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial, and microsomal (now designated as MAPEG) proteins. GSTs are present in eukaryotes and in prokaryotes, where they catalyze a variety of reactions and accept endogenous and xenobiotic substrates. GSTs can constitute up to 10% of cytosolic protein in some mammalian organs. GSTs catalyse the conjugation of reduced glutathione — via a sulfhydryl group — to electrophilic centers on a wide variety of substrates. This activity detoxifies endogenous compounds such as peroxidised lipids, as well as breakdown of xenobiotics. GSTs may also bind toxins and function as transport proteins, and, therefore, an early term for GSTs was "ligandin". The mammalian GST super-family consists of cytosolic dimeric isoenzymes of 45–55 kDa size that have been assigned to at least six classes: Alpha, Mu, Pi, Theta, Zeta and Omega
Catalogue number: DPAB0537
Hosts: Goat
Conjugates: Unconjugated
Gene: 2944
Target: GSTM1
Clonality: Polyclonal
Storage temp: Store at 2-8°C.

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