Goat anti Human MMP9 polyclonal antibody [Biotin]

Cat no: CABT-L268

Supplier: Creative Diagnostics

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Goat Anti-Human MMP9 antibody for ELISA(Det), WB. Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP-1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 maybe be divided into five distinct domains: a pro-domain which is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a proline-rich linker region, and a carboxyl terminal hemopexin-like domain.

Catalogue number:	CABT-L268
Reactivities:	Human
Hosts:	Goat
Conjugates:	Biotin
Gene:	4318
Target:	MMP9
Isotype:	IgG
Clonality:	Polyclonal
Storage temp:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

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Goat anti Human MMP9 polyclonal antibody [Biotin]

Cat no: CABT-L268

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