Goat anti Mouse IL1RN polyclonal antibody [Biotin]

Cat no: CABT-L317

Supplier: Creative Diagnostics

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Goat Anti-Mouse IL1RN polyclonal antibody for ELISA(Det), WB. IL-1ra was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The naturally-occurring, fully glycosylated form has an apparent molecular weight of about 25,000 Daltons. The protein shows 26% amino acid homology to IL-1 beta b and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells. In mouse, IL-1 RII does not bind IL-1ra. IL-1ra has been shown to block the inflammatory responses induced by IL-1 both in vitro and in vivo. Pre-clinical and clinical studies were done to test possible therapeutic applications for IL-1ra in the treatment of sepsis, rheumatoid arthritis and chronic myelogenous leukemia.

Catalogue number:	CABT-L317
Reactivities:	Mouse
Hosts:	Goat
Conjugates:	Biotin
Gene:	16181
Target:	IL1RN
Isotype:	IgG
Clonality:	Polyclonal
Storage temp:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

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Goat anti Mouse IL1RN polyclonal antibody [Biotin]

Cat no: CABT-L317

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