GP9, CT (GP9, Platelet glycoprotein IX, Glycoprotein 9, CD42a) (PE)

This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

036185-PE

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Munday, A.D., et al. J. Thromb. Haemost. 8(1):163-172(2010)\nMo, X., et al. J. Thromb. Haemost. 7(9):1533-1540(2009)\nMangin, P.H., et al. J. Thromb. Haemost. 7(9):1550-1555(2009)\nStrassel, C., et al. Haematologica 94(6):800-810(2009)\nZieger, B., et al. Hamostaseologie 29(2):161-167(2009)

Additional Info

Human, mouse

Alternative Names

GP9, Platelet glycoprotein IX, Glycoprotein 9, CD42a