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GPR72 (GPR83, Probable G-protein Coupled Receptor 83, G-protein Coupled Receptor 72, KIAA1540)

Cat no: G8600-76K

GPR72 (GPR83, Probable G-protein Coupled Receptor 83, G-protein Coupled Receptor 72, KIAA1540)

GPR72 is a 423aa protein and an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR72 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.\n\nApplications:\nSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilutions:\nWestern Blot: 0.5-2ug/ml\nImmunohistochemistry (Frozen, paraffin): 2.5-5ug/ml\nOptimal dilutions to be determined by the researcher.\n\nRecommended Positive Control:\nBrain\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

G8600-76K

Size

100ug

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Can, NHP

Form

Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. de Moerlooze, L. et al. Cytogenet Cell Genet. 90:146-150 (2000). 2. Hansen, W. et al. J. Immunol. 177:209-215 (2006).

Additional Info

Recognizes human GPR72. Species Crossreactivity: chimpanzee, canine, New World monkey, mouse and rat.

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SUPPLIER INFO

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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