GPR73A is a 7-transmembrane glycoprotein of the GPCR family. The extracellular portions of human GPR73A share 81% and 78% aa identity with corresponding portions of mouse GPR73A and human GPR73B, with non-identity mainly in the N-terminal sequences. Both GPR73A and GPR73B mediate the effects of prokineticins 1 and 2. This includes mitogenic regulation of angiogenesis in endocrine glands and stimulation of contraction in gastrointestinal smooth muscle.
Applications:
Suitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilutions:
Flow Cytometry: 2.5ug/ml labeled 10e6 human blood-derived monocytes.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.