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GPR83 (Probable G-protein Coupled Receptor 83, G-protein Coupled Receptor 72, GPR72, KIAA1540)

Cat no: G8600-76H


Supplier: United States Biological
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This mouse monoclonal antibody recognizes human GPR83 also known as G protein coupled receptor 83, GIR, G protein coupled receptor 72, and GPR72. GPR83 is a multi-pass membrane protein, belongs to the G-protein coupled receptor 1 family. GPR83 is an orphan GPR most homologous to the tachykinin and neuropeptide Y (NPY) receptors, has a predicted molecular weight 48kD. GPR83 is expressed in brain and upregulated in both murine and human Treg. GPR83 might be critically involved in the peripheral generation of Foxp3+ Treg cells in vivo. This monoclonal antibody has been shown to be useful for Western blotting. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 5ug/5ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8600-76H
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by immunoaffinity chromatography.
References: 1. De Moerlooze L., et al. 2000. Cytogenet. Cell Genet. 90:146. 2. Wiebke H., et al. 2006. J. Immunol. 177:209. 3. Sugimoto N, et al. 2006. Internat Immunol. 18:1197.
Additional info: Recognizes human GPR83.

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