Glutathione peroxidase 4 (GPX4) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
Sequence:
Human GPX4 (aa 1-197) is fused at the C-terminus to a His-tag.
Storage and Stability:
Short-term Storage: +4 degrees C
Long-term Storage: -20 degrees C
Working aliquots are stable for up to 3 months when stored at -20 degrees C.