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Grb14 (Growth Receptor-bound Protein 14)

Grb14 (Growth Receptor-bound Protein 14)

Cat no: G8960-30M

Supplier: United States Biological
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Grb14 is a 58 kDa protein that interacts in vivo with both the insulin receptor (IR) and Fibroblast Growth Factor Receptor 1 (FGFR1). The function of Grb14 is poorly understood, but overexpression of Grb14 suppresses insulin-induced DNA and glycogen synthesis, suggesting that it may be a modulator of IR signaling. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Positive Control: NIH/3T3 cell lysates Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8960-30M
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes human Grb14 (aa79-229). Sequence homology: mouse, rat.

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