Home  >  Products  >  GRIM-19 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, cell death-regulatory protein GRIM19, GRIM19, B16.6, CDA016, CGI-39, GRIM-19, CGI-39 protein,)

GRIM-19 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, cell death-regulatory protein GRIM19, GRIM19, B16.6, CDA016, CGI-39, GRIM-19, CGI-39 protein,)

Cat no: G8969-03


Supplier: United States Biological
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A novel gene, Genes associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G8969-03
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: As reported
P type: Pab
Purity: As reported
Alternative names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, cell death-regulatory protein GRIM19, GRIM19, B16.6, CDA016, CGI-39, GRIM-19, CGI-39 protein,
References: Angell, J.E. et al. J Biol Chem 2000 Oct 27; 275(43): 33416-26.
Additional info: Reacts with the human and mouse GRIM-19 protein.

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