Home  >  Products  >  Griseofulvin (Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533)
Griseofulvin (Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533)

Griseofulvin (Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533)

Cat no: G8970-80

Supplier: United States Biological
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Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important asect to the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy. Source: Penicillium sp. Apperance: White solid Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G8970-80
Size: 25mg
Purity: ~99%
References: 1. Studies in the biochemistry of microorganisms. LX. Griseofulvin - a metabolic product of Penicillium griseofulvum Dierkx. Oxford A.E. et al., Biochem J. 1939, 33, 240. 2. Griseofulvin inhibits fungal mitosis. Gull K. & Trinci A.P.J., Nature 1973, 244, 292. 3. Penicillium subgenus Penicillium: new taxonomic schemes, mycotoxins and other extrolites. Samson R.A. & Frisvad J.C., Studies in Mycology 2004, 49, 257.

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