Growth Hormone, Human, BioAssay(TM) ELISA Kit (HGH)

Human growth hormone (HGH, somatotropin) is a polypeptide secreted by the anterior pituitary. It is 191 amino acids in length and has a molecular mass of approximately 22,000 daltons. Its metabolic effects are primarity anabolic. HGH promotes protein conservation and is engaged in a wide range of mechanisms for protein synthesis. It also enhances glucose transport and facilitates glycogen storage. Its cascade of growth-promoting action is mediated by another family of peptide hormones, the somatomedins. HGH measurement is primarily of interest in the diagnosis and treatment of various forms of abnormal growth hormone secretion. Disorders caused by hyposecretion include dwarfism and unattained growth potential, and hypersecretion is associated with gigantism and acromegaly. Caution must be exercised in the clinical interpretation of growth hormone levels. These vary throughout the day, making it difficult to define a normal range or to judge an individual

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SPECIFICATIONS

Catalog Number

G9000-01P

Size

1Kit

Applications

ELISA

Reactivities

Hum

References

1. Van Wyk, J.J. and Underwood, L.E. Growth Hormone, Somatomedins and Growth Failure. Hospital Practice, 13: 57; 1978. 2. Fisher, D.A. Evaluation of Anterior Pituitary Function in: Radioimmunoassay Manual. Ed. Nicholas, A.L. and Nelson, J.C.P. 3498 Nichols Institute, 1977. 3. Goldfine, I.D. Medical Treatment of Acromegaly. Annual Revieew of Medicine. 29: 407; 1978. 4. Reichlin, S. et al. Hypothalamic Hormones. Annual Revieew of Medicine. 27: 359; 1976. 5. Rimoin, D.L. and Horton, W.A. Short Stature. J. Pediatrics. 92: 523; 1978.