Growth Hormone Releasing Peptide 2, Human (GH-Releasing Peptide 2)

Synthetic GHRP-2 is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 746.9 Dalton and a Molecular formula of C42H50N8O5.\n\nAmino Acid Composition: \nH-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2\n\nDimers and Aggregates: \nLess than 1% as determined by silver-stained SDS-PAGE gel analysis.\n\nProtein Content: \nProtein quantitation was carried out by two independent methods:\n1. UV spectroscopy at 280 nm .\n2. Analysis by RP-HPLC, using a standard solution of GHRP-2 as a Reference Standard.\n\nSolubility: \nIt is recommended to reconstitute the lyophilized GHRP-2 in sterile 18MOmega-cm H2O not less than 100microg/ml, which can then be further diluted to other aqueous solutions.\n\nStability: \nLyophilized GHRP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -180C. Upon reconstitution GHRP-2 should be stored at 40C between 2-7 days and for future use below -180C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

G9000-40

Size

5mg

Form

Supplied as a lyophilized powder without additives.

Purity

(same/more than) 98% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.

References

1. KP-102 (growth hormone-releasing peptide-2) attenuates ischemia/reperfusion injury in isolated rat hearts.\n\nNaunyn Schmiedebergs Arch Pharmacol 2006 Jun 14;\n\n2. Tissue deiodinase activity during prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone-releasing peptide-2.\n\nEndocrinology 2005 Dec;146(12):5604-11\n\n3. Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.\n\nAm J Physiol Endocrinol Metab 2005 Nov;289(5):E762-7\n\n4. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.\n\nJ Clin Endocrinol Metab 2005 Feb;90(2):611-4\n\n5. Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats.\n\nAm J Physiol Endocrinol Metab 2005 Mar;288(3):E486-92\n\n6. Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN.\n\nDrugs R D 2004;5(4):236-9