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GSK360A

GSK360A

Cat no: 012982

Supplier: United States Biological
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GSK360A orally active HIF-PHD inhibitor. GSK360A exerts systemic and local effects by stabilizing HIF-1a signaling and improves long-term ventricular function, remodeling, and vascularity in a model of established ventricular dysfunction. These findings suggest that GSK360A may be suitable for the treatment of post-MI remodeling and heart failure. Form: Beige Solid Melting Point: 195-197 degrees C Solubility: Methanol
Catalogue number: 012982
Size: 5mg
Form: Beige Solid
Alternative names: N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine; N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine;
References: Bao, W.-K. et al.: J. Cardio. Pharmacol., 56, 147 (2010);

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