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GSK3a (Glycogen Synthase Kinase-3 alpha, GSK-3 alpha)

GSK3a (Glycogen Synthase Kinase-3 alpha, GSK-3 alpha)

Cat no: G8170-43J

Supplier: United States Biological
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GSK3 is a serine/threonine kinase with a proline-directed substrate preference. Apart from phosphorylating and inhibiting glycogen synthase (GS), various other substrates for GSK3 have been identified that includes protein phosphatase inhibitor 2, ATP-citrate lyase, tau protein, beta-catenin, c-Myc, c-Jun, cAMP response element-binding protein, CCAAT/enhancer-binding protein- , and initiation factor eukaryotic initiation factor. In human, GSK3 exists in two isoforms a-isoform and b-isoform, encoded by two distinct genes located on chromosomes 19q13.1
Catalogue number: G8170-43J
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Theodore, PC. et al. Endocrinology. 148:4393-4399 (2006).
Additional info: Recognizes human GSK3a. Species Crossreactivity: mouse and rat.

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