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GSTP1 (Glutathione S-transferase P, GST Class-pi, GSTP1-1, FAEES3, GST3)

GSTP1 (Glutathione S-transferase P, GST Class-pi, GSTP1-1, FAEES3, GST3)

Cat no: G8135-25L

Supplier: United States Biological
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Human glutathione S-transferases (GSTs) are a large multigene family of isoenzymes, which catalyse the conjugation of glutathione to electrophilic substrates. These enzymes are involved in the detoxification of both endogenous and exogenous electrophiles, which can react with cellular components such as DNA. The modification of DNA by reactive compounds can initiate carcinogenesis and the GSTs are believed to play a role in cancer prevention by inactivating carcinogens. There are four major structural classes of mammalian cytosolic GSTs (alpha, mu, pi and theta). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.01-0.03ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Kidney lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8135-25L
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Malerba G, Pignatti PF. A review of asthma genetics: gene expression studies and recent candidates. J Appl Genet. 2005;46(1):93-104. Review. PMID: 15741670.
Additional info: Recognizes human GSTP1. Species sequence homology: canine, mouse, rat.

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