Hantavirus, nucleoprotein (Andes Virus)

The members of the Hantavirus genus of the family Bunyaviridae are spherical, enveloped viruses containing tripartite negative-sense RNA as their genome. The three genomic RNA segments, designated L, M, and S, encode an RNA-dependent RNA polymerase, envelope glycoproteins (G1 and G2), and nucleocapsid (N) protein, respectively. Hantavirus infections can cause two serious and often fatal human diseases, hemorrhagic fever with renal syndrome and hantaviral pulmonary syndrome, characterized by lung damage and cardiac dysfunction. Humans are infected with hantaviruses from rodent reservoirs that are persistently infected without signs of disease.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilutions:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

H1809-02

Size

100ug

Applications

ELISA, WB

Hosts

Mouse

Form

Supplied as a liquid in PBS.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG3

References

1. B. Hjelle et al., (1994). Journal of Gen. Virology 75, 2881-2888. 2. B. Hjelle et al., (1995). Critical Reviews in Clin. Lab. Sciences 32, 469-508.

Additional Info

Recognizes the nucleoprotein region aa58-87 of Andes virus.