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Haptoglobin, beta, Recombinant, Human

Cat no: H1820-01F

Haptoglobin, beta, Recombinant, Human

Recombinant Haptoglobin b-chain comprises a 245aa fragment (162-406) corresponding to the mature haptoglobin b-chain and is expressed in E. coli with an amino-terminal hexahistidine tag.\n\nHaptoglobin is a glycoprotein secreted in the blood plasma that binds free haemoglobin thereby inhibiting its oxidative activity and preventing iron loss following haemolysis. Haptoglobin also regulates the activity of many cell types of the immune system and is an extracellular chaperone. Haptoglobin is produced mostly by hepatocytes but also by other tissues: e.g. skin, lung and kidney.\n\nApplications: \nSuitable for antigenic applications in immunological protocols as well as calibrators and controls. Other applications have not been tested. \n \nRecommended Dilutions:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H1820-01F

Size

10ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 50% glycerol.

Purity

~90% by SDS-PAGE

References

1. Yang, F. et al., Proc. Natl. Acad. Sci. USA 80; 5875-5879 (1983). 2. Kurosky, A. et al., Proc. Natl. Acad. Sci. USA 77; 3388-3392 (1980).

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