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HAX1, Recombinant, Human, aa1-279, His-Tag (HCLS1 Associated Protein X-1 Isoform A, HCLSBP1, HS1BP1, SCN3)

Cat no: 137074

HAX1, Recombinant, Human, aa1-279, His-Tag (HCLS1 Associated Protein X-1 Isoform A, HCLSBP1, HS1BP1, SCN3)

HAX1 is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with F-actin-binding protein, cortactin. It is associated with autosomal recessive severe congenital neutropenia, also known as Kostmann syndrome. \n\nSource: \nRecombinant protein corresponding to human HAX1, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~33.7kD (299aa) (MALDI-TOF)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MSLFDLFRGF FGFPGPRSHR DPFFGGMTRD EDDDEEEEEE GGSWGRGNPR FHSPQHPPEE FGFGFSFSPG GGIRFHDNFG FDDLVRDFNS IFSDMGAWTL PSHPPELPGP ESETPGERLR EGQTLRDSML KYPDSHQPRI FGGVLESDAR SESPQPAPDW GSQRPFHRFD DVWPMDPHPR TREDNDLDSQ VSQEGLGPVL QPQPKSYFKS ISVTKITKPD GIVEERRTVV DSEGRTETTV TRHEADSSPR GDPESPRPPA LDDAFSILDL FLGRWFRSR\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137074

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol, 0.1M NaCl.

Purity

~80% (SDS-PAGE)

References

1. Modem S. et al. (2008) J Cell Physiol. 214:14-19. 2. Klein C. et al. (2007) Nat Genet. 39:86-92.

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