HBG1, Recombinant, Human, aa1-147, His-Tag (Hemoglobin Subunit Gamma-1, HBGA, HBGR, HSGGL1, PRO2979)

Supplier:

United States Biological

Cat no: 137076

HBG1, Recombinant, Human, aa1-147, His-Tag (Hemoglobin Subunit Gamma-1, HBGA, HBGR, HSGGL1, PRO2979)

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5' - epsilon

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SPECIFICATIONS

Catalog Number

137076

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 10% glycerol.

Purity

~85% (SDS-PAGE)

References

1. Huisman, TH Kutlar, F et al: Hemoglobin 1991, 15(5):349-79. 2. Loudianos, G Moi, P et al: Hemoglobin. 1992, 16(6):503-9.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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