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hCD70-muCD8 Fusion Protein (human CD70-murine CD8 Fusion Protein)

Cat no: C2425-01Q

hCD70-muCD8 Fusion Protein (human CD70-murine CD8 Fusion Protein)

Human CD70 (TNFSF7) is the ligand for CD27 (TNFRSF7) and is notably absent on resting lymphocytes. CD70 is expressed after activation on about 20% of T cells and on about 70% of B cells. Recombinant CD70-muCD8 binds to cell surface CD27 on human peripheral blood leukocytes.\n\nMolecular Structure:

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SPECIFICATIONS

Catalog Number

C2425-01Q

Size

25ug

Applications

ELISA, FC

Form

Supplied as liquid in 50mM sodium phosphate pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 0.5mg/ml gentamicin sulfate.

Purity

Purified by size exclusion.

References

1. R.Q. Hintzen, et al, (1994) J Immunol 152: 1762-1773, 2. M.R. Bowman, et al, (1994) J Immunol 152: 1756-1761, 3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1137-1138, 4. K. Agematsu, et al, (1995) J Immunol 154: 3627-3635, 5. T. F. Rowley , A Al-Shamkhani, (2004) J Immunol 172: 6039-6046, 6. J. M.Carr, D. T. Fearon, et al. (2006) PNAS:103(51):19454-19459

Alternative Names

CD27 L, CD70 Molecule

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