HCV-Core Antibody

Cat no: 250683

Supplier: ABBIOTEC

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Description
Additional Information

The p21 core protein from Hepatitis C virus (HCV) packages viral RNA to form a viral nucleocapsid and promotes virion budding . p21 modulates viral translation initiation and regulates many host cellular activities by interacting with HCV IRES and 40S ribosomal subunit. p21 also regulates host cellular functions that prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. p21 plays an important role in the virus-mediated cell transformation leading to hepatocellular carcinomas.

Catalogue number:	250683
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P26664
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of HCV p21 core protein.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Genome polyprotein Hepatitis C virus; Core protein p21; Core protein p19; HCV Capsid protein C