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MtoZ Biolabs

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HCV-Core Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250683

HCV-Core Antibody

The p21 core protein from Hepatitis C virus (HCV) packages viral RNA to form a viral nucleocapsid and promotes virion budding . p21 modulates viral translation initiation and regulates many host cellular activities by interacting with HCV IRES and 40S ribosomal subunit. p21 also regulates host cellular functions that prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. p21 plays an important role in the virus-mediated cell transformation leading to hepatocellular carcinomas.

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SPECIFICATIONS

Catalog Number

250683

Size

0.1 mg

Applications

IHC

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of HCV p21 core protein.

Isotype

Rabbit Ig

Accession

P26664

Additional Info

Genome polyprotein Hepatitis C virus; Core protein p21; Core protein p19; HCV Capsid protein C

SUPPLIER INFO

ABBIOTEC

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