HDAC3 (3A7B) Antibody

Cat no: 252812

Supplier: ABBIOTEC

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Description
Additional Information

HDAC3 (Histone deacetylase 3) is a histone deacetylase protein. Histones play a critical role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Catalogue number:	252812
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	O15379
Antigen:	Purified recombinant fragment of HDAC3(aa224-428) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3A7B5
Additional info:	Histone deacetylase 3; HD3; RPD3-2; SMAP45; HDAC3