HER-2 (9B9D) Antibody

Cat no: 252700

Supplier: ABBIOTEC

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Description
Additional Information

C-erbB-2 (HER2) is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. HER2 has no ligand binding domain, therefore cannot bind growth factors. However, HER2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

Catalogue number:	252700
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P04626
Antigen:	Purified recombinant fragment of HER-2 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Clonality:	9B9D8
Additional info:	Receptor tyrosine protein kinase erbB2; p185erbB2; C-erbB-2; Neu proto-oncogene; Tyrosine kinase-type cell surface receptor HER2; MLN 19; ERBB2; HER2; NEU; NGL