HERG Antibody

Cat no: 252174

Supplier: ABBIOTEC

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Description
Additional Information

Potassium voltage-gated channel subfamily H member 2 (HERG) is the pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. The HERG channel properties are modulated by cAMP and subunit assembly. HERG mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. Defects in HERG are the cause of long QT syndrome type 2 (LQT2). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to e, Xenopus/Amphibian,ercise or emotional stress.

Catalogue number:	252174
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q12809
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HERG.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Potassium voltage-gated channel subfamily H member 2; Voltage-gated potassium channel subunit Kv11.1; Ether-a-go-go-related gene potassium channel 1; Ether-a-go-go-related protein 1; Eag-related protein 1; ERG-1; hERG-1; hERG1; H-ERG; Eag homolog; KCNH2; ERG; ERG1; HERG