Kaposi's sarcoma-associated herpesvirus (HHV-8) is one of seven currently known human cancer viruses, or oncoviruses. KSHV is a herpesvirus, and is a large double-stranded DNA virus with a protein covering that packages its nucleic acids, called the capsid, which is then surrounded by an amorphous protein layer called the tegument, and finally enclosed in a lipid envelope derived in part from the cell membrane. KSHV has a genome which is appro, Xenopus/Amphibian,imately 165,000 nucleic acid bases in length. This antibody recognizes transcription activator ORF50 (HHV-8 ORF50).