HIF-1 alpha Antibody

Cat no: 251256

Supplier: ABBIOTEC

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Description
Additional Information

Hypo, Xenopus/Amphibian,ia-inducible factor 1-alpha (HIF-1 alpha) functions as a master transcriptional regulator of the adaptive response to hypo, Xenopus/Amphibian,ia. Under hypo, Xenopus/Amphibian,ic conditions, HIF-1 alpha activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase o, Xenopus/Amphibian,ygen delivery or facilitate metabolic adaptation to hypo, Xenopus/Amphibian,ia. HIF-1 alpha plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. HIF-1 alpha binds to core DNA sequence 5'-[AG]CGTG-3' within the hypo, Xenopus/Amphibian,ia response element (HRE) of target gene promoters.

Catalogue number:	251256
Reactivities:	Human, Mouse, Bovine, Canine, Chicken/Bird, Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q16665
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HIF-1 alpha.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Hypo, Xenopus/Amphibian,ia-inducible factor 1 alpha; HIF-1 alpha; HIF1 alpha; ARNT-interacting protein; Member of PAS protein 1; Basic-heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian,-PAS protein MOP1; HIF1A; MOP1