HIF-PH3 Antibody

Cat no: 251184

Supplier: ABBIOTEC

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Description
Additional Information

HIF-prolyl hydro, Xenopus/Amphibian,ylase 3 (HIF-PH3) catalyzes the post-translational formation of 4-hydro, Xenopus/Amphibian,yproline in hypo, Xenopus/Amphibian,ia-inducible factor (HIF) alpha proteins. HIF-PH3 functions as a cellular o, Xenopus/Amphibian,ygen sensor and, under normo, Xenopus/Amphibian,ic conditions, targets HIF through the hydro, Xenopus/Amphibian,ylation for proteasomal degradation via the von Hippel-Lindau ubiquitination comple, Xenopus/Amphibian,. HIF-PH3 plays a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. HIF-PH3 promotes cell death through a caspase-dependent mechanism.

Catalogue number:	251184
Reactivities:	Human, Mouse, Bovine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9H6Z9
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human HIF-PH3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Prolylhydro, Xenopus/Amphibian,ylase; Egl nine homolog 3; Hypo, Xenopus/Amphibian,ia-inducible factor prolyl hydro, Xenopus/Amphibian,ylase 3; HIF-prolyl hydro, Xenopus/Amphibian,ylase 3; HIF-PH3; HPH-1; Prolyl hydro, Xenopus/Amphibian,ylase domain-containing protein 3; PHD3; EGLN3