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HLA Class 2 Antigen DR

Cat no: H6099-95W

HLA Class 2 Antigen DR

The antibody is useful for detection of HLA-DR positive B-cells, T-cells, monocytes in cell suspensions and frozen sections.\n\nApplications: \nSuitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H6099-95W

Size

100ug

Applications

FC, IP

Hosts

Mouse

Reactivities

Hum

Form

15mM Sodium Azide; PBS. pH 7.4

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG3

References

This product has been used in:Horejsi V et al. Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens. Tissue Antigens 28:288-97 (1986). <PUBMED:2435017> Momburg F et al. B-cell lymphomas of high-grade malignancy frequently lack HLA-DR, -DP and -DQ antigens and associated invariant chain. Int J Cancer 40:598-603 (1987). <PUBMED:3316049>

Additional Info

The antibody binds to a common monomorphic determinant of HLA-DR which is dependent on the association of the heavy and the light chain of HLA-DR molecules. Species Crossreactivity: Crossreacts with Human. Not yet tested in other species.

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