HLA-G Peptide

Cat no: BS60401P

Supplier: Bioworld Technology, Inc.

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Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an a or heavy chain, and a non-covalently associated protein, b-2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange.

Catalogue number:	BS60401P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P17693
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide HLA-G. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; MHC class I antigen G; HLA-G; HLA-6.0; HLAG
Additional info:	This peptide can be used with studies using BS60401 HLA-G pAb.

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HLA-G Peptide

Cat no: BS60401P

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