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HLX1 (Q338) Peptide

Cat no: BS2658P

HLX1 (Q338) Peptide

HLX1 (homeobox protein HB24) is a 488 amino acid protein encoded by the human gene HLX1. HLX1 belongs to the H2.0 homeobox family and contains one homeobox DNA-binding domain. HLX1 is considered a diverged human homeodomain-containing protein known to be expressed in hematopoietic progenitors and activated lymphocytes. HLX1 is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. It is also involved in embryogenesis and hematopoiesis. Overexpression of HLX1 will cause a marked increase in activated T cells/thymocytes and interleukin-2 receptor expression. Overexpression will also impair the normal development of CD4+ T cells and will prevent the thymus from undergoing normal involution.

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SPECIFICATIONS

Catalog Number

BS2658P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide HLX1 (Q338). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q14774

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2658 HLX1 (Q338) pAb.

Alternative Names

H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HLX; HLX; Homeobox protein HB24; Homeobox protein HLX1;

SUPPLIER INFO

Bioworld Technology, Inc.

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