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HNF4(alpha)/(gamma) (K127) pAb

HNF4(alpha)/(gamma) (K127) pAb

Cat no: BS1992

Supplier: Bioworld Technology, Inc.
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HNF-1 ((alpha) and (beta)), HNF-3 ((alpha), (beta) and (gamma)), HNF-4 ((alpha) and (gamma)), and HNF-6 compose, in part, a homoeprotein family designated the Hepatocyte Nuclear Factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3(alpha), HNF-3(beta) and HNF-3(gamma) regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3(alpha) and HNF-3(beta) have also been shown to be involved in gastrulation events such as body axis formation. HNF-4(alpha) and HNF-4(gamma) have been shown to be important for early embryo development. HNF-4(alpha) is expressed in liver, kidney, pancreas, small intestine, testis and colon; and HNF-4(gamma) is expressed in each of these tissues except liver.
Catalogue number: BS1992
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P41235
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 100-150 of Human HNF4(alpha).
Species: HNF-4(alpha)/(gamma) (K127) pAb detects endogenous levels of HNF-4(alpha)/(gamma) protein.
Molecular weight: ~ 52 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: HNF 4 alpha; HNF 4; HNF-4-alpha; HNF4; HNF4A; HNF4A; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; MODY 1; MODY; MODY1; NR2A1; NR2A21;
Additional info: For research use only, not for use in diagnostic procedure.

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