Established in 1994 from the peripheral blood of a 47-year-old woman with acute myeloid leukemia (AML FAB M4) secondary to previous myelodysplastic syndromes (MDS), specifically chronic myelomonocytic leukemia (CMML); described to carry the t(3;3)(q21;q26) leading to MECOM (EVI1) overexpression and the Philadelphia chromosome t(9;22) expressing both P190 and P210 BCR-ABL1 chimeric transcripts