Biopharmaceuticals, drugs produced by living cells, have revolutionized the treatment of various diseases since Eli Lilly and Company's introduction of the first human recombinant protein, Humulin (human insulin), in 1982. To date, over 200 biopharmaceuticals have been approved, encompassing hormones, growth factors, blood factors, vaccines, and monoclonal antibodies (mAbs), with mAbs being the predominant category.