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Hox B9 (Homeobox HB9, Homeo-box HB9, Homeobox Protein B9, Homeobox Protein HB9, HB9, HLXB9, HOXHB9, Hox 2.5, Hox 2E, Sacral Agenesis Autosomal Dominant (Currarino Triad), SCRA1)

Cat no: H7023-15T3

Hox B9 (Homeobox HB9, Homeo-box HB9, Homeobox Protein B9, Homeobox Protein HB9, HB9, HLXB9, HOXHB9, Hox 2.5, Hox 2E, Sacral Agenesis Autosomal Dominant (Currarino Triad), SCRA1)

HB9 are sequence-specific DNA-binding proteins that have been implicated in the control of gene expression both in developing as well as in adult tissues; a putative transcription factor involved in pancreas development and function. HB9, was found to be highly expressed in bone marrow cells enriched for CD34-positive cells, present at low levels in unfractionated bone marrow cells, and essentially undetectable in bone marrow cells depleted of CD34 cells. Studies show differentiation of CD34-positive cells along a specific cell lineage likely requires down regulation of both HB24 and HB9. \n \nApplications:\nSuitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilutions:\nWestern Blot: 1:1000-1:10,000 \nImmunoprecipitation: 1:50 \nOptimal dilutions to be determined by the researcher.\n\nPositive Controls:\nMOLT-4 and Raji cell lysates\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. \n\nManufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.

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SPECIFICATIONS

Catalog Number

H7023-15T3

Size

100ul

Applications

IHC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.4, 0.05% BSA, 0.01% sodium azide, 50% glycerol.

P Type

Mab

Purity

Supernatant

Isotype

IgG

References

1. Deguchi Y, et al. Blood 78(2):323-8, 1991

Additional Info

Recognizes human Hox B9 at ~48kD. \nSpecies Crossreactivity: mouse. Does not crossreact with rat

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