HRas Antibody

Cat no: 251442

Supplier: ABBIOTEC

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Description
Additional Information

GTPase HRas (HRas) binds GDP/GTP and possess intrinsic GTPase activity. HRas alternates between an inactive form bound to GDP and an active form bound to GTP. HRas is activated by a guanine nucleotide-e, Xenopus/Amphibian,change factor (GEF) and inactivated by a GTPase-activating protein (GAP). Defects in HRAS are the cause of Costello syndrome (COSTS), also known as faciocutaneoskeletal syndrome. Costello syndrome is a rare condition characterized by prenatally increased growth,Porcineostnatal growth deficiency,Mouse,ental retardation, distinctive facial appearance, cardiovascular abnormalities (typically pulmonic stenosis, hypertrophic cardiomyopathy and/or atrial tachycardia), tumor predisposition, and skin and musculoskeletal abnormalities.

Catalogue number:	251442
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P01112
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human HRas.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	HRas; GTPase HRas; Transforming protein p21; p21ras; H-Ras-1; c-H-ras; Ha-Ras