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HSD17B14, aa1-270, Recombinant, Human (17-beta-hydroxysteroid dehydrogenase 14)

Cat no: H9117-83B

HSD17B14, aa1-270, Recombinant, Human (17-beta-hydroxysteroid dehydrogenase 14)

HSD17B14, also known as 17-beta-hydroxysteroid dehydrogenase 14, belongs to the 17-beta-HSD family of proteins, which regulate the availability of steroids within various tissues rough out the body. It exists as a homotetramer that localizes to the cytoplasm and is highly expressed in brain, placenta, liver and kidney.\n\nSource:\nRecombinant human HSD17B14 protein, fused to His-tag at N-terminus, expressed in E.coli.\n\nAA Sequence:\nMRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMATG TRYAGKVVVV TGGGRGIGAG IVRAFVNSGA RVVICDKDES GGRALEQELP\nGAVFILCDVT QEDDVKTLVS ETIRRFGRLD CVVNNAGHHP PPQRPEETSA QGFRQLLELN LLGTYTLTKL ALPYLRKSQG NVINISSLVG \nAIGQAQAVPY VATKGAVTAM TKALALDESP YGVRVNCISP GNIWTPLWEE LAALMPDPRA TIREGMLAQP LGRMGQPAEV GAAAVFLASE\nANFCTGIELL VTGGAELGYG CKASRSTPVD APDIPS\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

H9117-83B

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 20% glycerol, 0.1M sodium chloride, 1mM DTT.

Purity

~95% (SDS-PAGE)

References

1. Grimwood J., et al. (2004), Nature., 428: 529-535. 2. Lukacik P., et al. (2007). Biochem. J., 402: 419-427.

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