Home  >  Products  >  HTR3A (5-hydroxytryptamine Receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine Receptor 3, 5-HT-3, 5-HT3R, Serotonin Receptor 3A, Serotonin-gated Ion Channel Receptor, 5HT3R, HTR3)
HTR3A (5-hydroxytryptamine Receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine Receptor 3, 5-HT-3, 5-HT3R, Serotonin Receptor 3A, Serotonin-gated Ion Channel Receptor, 5HT3R, HTR3)

HTR3A (5-hydroxytryptamine Receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine Receptor 3, 5-HT-3, 5-HT3R, Serotonin Receptor 3A, Serotonin-gated Ion Channel Receptor, 5HT3R, HTR3)

Cat no: S1001-19R

Supplier: United States Biological
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This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. Applications: Suitable for use in ELISA, Immunocytochemistry, Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.3-1ug/ml, observed in human colon lysates on ~55kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1001-19R
Reactivities: Human, Rat
Hosts: Goat
Applications: ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Lu CL, Hsieh JC, Dun NJ, Oprea TI, Wang PS, Luo JC, Lin HC, Chang FY, Lee SD. Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats. Gastroenterology. 2009 Sep;137(3):1040-50.
Additional info: Recognizes HTR3A. Species Crossreactivity: Human and rat.

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