Human 182 kDa tankyrase-1-binding protein (TNKS1BP1) ELISA Kit

TNKS1BP1, has a calculated molecular mass of 182 kD. It is predicted to contain 2 basic regions at its N and C termini and a large internal acidic region. The C terminus also contains 2 potential nuclear localization signals. Northern blot analysis detected transcripts of 7, 4.4, and 2.3 kb in multiple tissues, with highest expression in testis, ovary, and lung, and minimal expression in brain and peripheral blood leukocytes. By immunolocalization of endogenous TAB182 in 2 human cell lines, Seimiya and Smith (2002) found TAB182 in the cytoplasm, where it colocalized with cortical actin, and in the nucleus. The nuclear staining was similar to that found for heterochromatin proteins. In a synchronized population of HeLa cells, TAB182 associated with chromosomes throughout mitosis.

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SPECIFICATIONS

Catalog Number

KTE60194

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

85456

Accession

Q9C0C2

Additional Info

Human 182 kDa tankyrase-1-binding protein (TNKS1BP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNKS1BP1. No significant cross-reactivity or interference between Human TNKS1BP1 and analogues was observed.