Human 20S proteasome (20SP) ELISA Kit

The number and diversity of subunits contained in the 20S core particle depends on the organism; the number of distinct and specialized subunits is larger in multicellular than unicellular organisms and larger in eukaryotes than in prokaryotes. All 20S particles consist of four stacked heptameric ring structures that are themselves composed of two different types of subunits; ? subunits are structural in nature, whereas ? subunits are predominantly catalytic. The outer two rings in the stack consist of seven ? subunits each, which serve as docking domains for the regulatory particles and the alpha subunits N-termini form a gate that blocks unregulated access of substrates to the interior cavity. The inner two rings each consist of seven ? subunits and contain the protease active sites that perform the proteolysis reactions. The size of the proteasome is relatively conserved and is about 150 angstroms (Г…) by 115 Г….

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SPECIFICATIONS

Catalog Number

KTE62530

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human 20S proteasome (20SP) ELISA Kit has high sensitivity and excellent specificity for detection of Human 20SP. No significant cross-reactivity or interference between Human 20SP and analogues was observed.